Adelaide midfielder Brodie Smith has been ruled out of the Crows' Round 10 clash with Melbourne after failing a late fitness test.

Smith failed to overcome a heavy knock to his right knee sustained against North Melbourne in Round Nine.

Forward Ben Crocker will replace Smith in the final 22.

Crocker, Paul Seedsman, Harry Schoenberg and Fischer McAsey will start the game on the interchange.

Crows coach Matthew Nicks made eight changes to the side that lost to the Kangaroos on Saturday, including handing debuts to Lachlan Sholl and Harry Schoenberg.

First bounce is at 7.40pm ACST and will be televised live on Channel 7 in Adelaide.

The game will be televised live nationwide on Fox Footy.